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Volume 11, Issue 1, Pages 119-140 (February 2007)


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Medical Treatment of Non-alcoholic Steatohepatitis

Abdurrahman Kadayifci, MDabCorresponding Author Informationemail address, Raphael B. Merriman, MB, MRCPIa, Nathan M. Bass, MB, ChB, PhDa

There is no proven medical treatment of non-alcoholic steatohepatitis (NASH). Most prior therapeutic trials have had methodologic limitations. Insulin sensitizers are the more promising therapeutic candidates among categories that include antioxidants, lipid-lowering agents, and antiobesity drugs. The future will see the evaluation of novel agents and a comprehensive treatment strategy that addresses the risk factors for the metabolic syndrome. This article reviews the current status of medical management options for NASH.

a Division of Gastroenterology, Department of Medicine, 513 Parnassus Avenue, Room S-357, University of California, San Francisco, San Francisco, CA 94143-0538, USA

b Division of Gastroenterology, Department of Medicine, University of Gaziantep, 27310 Gaziantep, Turkey

Corresponding Author InformationCorresponding author. Division of Gastroenterology, Department of Medicine, 513 Parnassus Avenue, Room S-357, University of California, San Francisco, San Francisco, CA 94143-0538.

PII: S1089-3261(07)00002-5

doi:10.1016/j.cld.2007.02.001


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