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References
- Idiosyncratic drug hepatotoxicity.Nat Rev Drug Discov. 2005; 4: 489-499
- Drug-induced liver injury.Handb Exp Pharmacol. 2010; : 3-27
- Unrecognized acetaminophen toxicity as a cause of indeterminate acute liver failure.Hepatology. 2011; 53: 567-576
- Acetaminophen-induced acute liver failure: results of a United States multicenter, prospective study.Hepatology. 2005; 42: 1364-1372
- Drug-induced liver injury.Drug Saf. 2007; 30: 277-294
- Relationship between daily dose of oral medications and idiosyncratic drug-induced liver injury: search for signals.Hepatology. 2008; 47: 2003-2009
- Oral medications with significant hepatic metabolism at higher risk for hepatic adverse events.Hepatology. 2010; 51: 615-620
- Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor.J Exp Med. 1998; 187: 1477-1485
- RIP kinases at the crossroads of cell death and survival.Cell. 2009; 138: 229-232
- The role of the kinases RIP1 and RIP3 in TNF-induced necrosis.Sci Signal. 2010; 3: re4
- Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha.Cell. 2009; 137: 1100-1111
- Necrostatin-1 attenuates mitochondrial dysfunction in neurons and astrocytes following neonatal hypoxia-ischemia.Neuroscience. 2012; 219: 192-203
- Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation.Cell. 2009; 137: 1112-1123
- Virus inhibition of RIP3-dependent necrosis.Cell Host Microbe. 2010; 7: 302-313
- c-Jun N-terminal kinase plays a major role in murine acetaminophen hepatotoxicity.Gastroenterology. 2006; 131: 165-178
- Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.J Biol Chem. 2010; 285: 8244-8255
- Deletion of apoptosis signal-regulating kinase 1 attenuates acetaminophen-induced liver injury by inhibiting c-Jun N-terminal kinase activation.Gastroenterology. 2008; 135: 1311-1321
- Critical role for mixed-lineage kinase 3 in acetaminophen-induced hepatotoxicity.Mol Pharmacol. 2012; 82: 1001-1007
- Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes.Am J Physiol Cell Physiol. 2008; 295: C50-C63
- In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.Drug Metab Dispos. 2012; 40: 130-138
- Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.Toxicol Sci. 2010; 118: 485-500
- Nrf2:INrf2 (Keap1) signaling in oxidative stress.Free Radic Biol Med. 2009; 47: 1304-1309
- Nrf2 signaling and cell survival.Toxicol Appl Pharmacol. 2010; 244: 37-42
- Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2-Cul3-Rbx1 complex to allow normal Nrf2 activation and repression.J Cell Sci. 2012; 125: 1027-1038
- Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.Biol Chem. 2006; 387: 1311-1320
- Different electrostatic potentials define ETGE and DLG motifs as hinge and latch in oxidative stress response.Mol Cell Biol. 2007; 27: 7511-7521
- The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system.Hepatology. 2008; 48: 1292-1301
- The Nrf2-Keap1 defence pathway: role in protection against drug-induced toxicity.Toxicology. 2008; 246: 24-33
- How to protect against acetaminophen: don't ask for JUNK.Gastroenterology. 2008; 135: 1047-1051
- Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.EMBO J. 1998; 17: 2596-2606
- Regulation of JNK signaling by GSTp.EMBO J. 1999; 18: 1321-1334
- c-Jun N-terminal kinase (JNK)-dependent acute liver injury from acetaminophen or tumor necrosis factor (TNF) requires mitochondrial Sab protein expression in mice.J Biol Chem. 2011; 286: 35071-35078
- The role of mitochondria in apoptosis*.Annu Rev Genet. 2009; 43: 95-118
- Mitochondria and ischemia/reperfusion injury.Ann N Y Acad Sci. 2005; 1047: 248-258
- The BCL-2 protein family: opposing activities that mediate cell death.Nat Rev Mol Cell Biol. 2008; 9: 47-59
- Cell biology. Cellular demolition and the rules of engagement.Science. 2007; 315: 776-777
- RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis.Science. 2009; 325: 332-336
- The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways.Cell. 2012; 148: 228-243
- Investigations of the N-hydroxylation of 3'-hydroxyacetanilide, a non-hepatotoxic positional isomer of acetaminophen.Drug Metab Dispos. 1989; 17: 355-359
- Characterization of glutathione conjugates of reactive metabolites of 3'-hydroxyacetanilide, a nonhepatotoxic positional isomer of acetaminophen.Chem Res Toxicol. 1989; 2: 41-45
- Hepatic protein arylation, glutathione depletion, and metabolite profiles of acetaminophen and a non-hepatotoxic regioisomer, 3'-hydroxyacetanilide, in the mouse.Drug Metab Dispos. 1990; 18: 765-770
- Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane.Cell. 2002; 111: 331-342
- Cytochrome c release from mitochondria proceeds by a two-step process.Proc Natl Acad Sci U S A. 2002; 99: 1259-1263
- Troglitazone-induced hepatic mitochondrial proteome expression dynamics in heterozygous Sod2(+/−) mice: two-stage oxidative injury.Toxicol Appl Pharmacol. 2008; 231: 43-51
- Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model of idiosyncratic drug toxicity.Toxicol Appl Pharmacol. 2009; 238: 150-159
- Sensitivity of liver injury in heterozygous Sod2 knockout mice treated with troglitazone or acetaminophen.Toxicol Pathol. 2009; 37: 193-200
- Mitochondrial fission, fusion, and stress.Science. 2012; 337: 1062-1065
- PINK1- and Parkin-mediated mitophagy at a glance.J Cell Sci. 2012; 125: 795-799
- Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL.J Cell Biol. 2010; 191: 933-942
- PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding.J Cell Biol. 2013; 200: 163-172
- PINK1 is selectively stabilized on impaired mitochondria to activate Parkin.PLoS Biol. 2010; 8: e1000298
- Mitochondrial dynamics and apoptosis.Genes Dev. 2008; 22: 1577-1590
- Membrane remodeling induced by the dynamin-related protein Drp1 stimulates Bax oligomerization.Cell. 2010; 142: 889-901
- Dealing with stress.Hepatology. 2012; 55: 3-13
- HLA association of amoxicillin-clavulanate–induced hepatitis.Gastroenterology. 1999; 117: 1181-1186
- Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles.Gastroenterology. 2011; 141: 338-347
- Co-amoxiclav jaundice: clinical and histological features and HLA class II association.Gut. 2000; 47: 717-720
- A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury.Nat Genet. 2010; 42: 711-714
- HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin.Nat Genet. 2009; 41: 816-819
- Sterile inflammation in the liver.Gastroenterology. 2012; 143: 1158-1172
- High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo.Toxicol Sci. 2009; 112: 521-531
- Ranitidine treatment during a modest inflammatory response precipitates idiosyncrasy-like liver injury in rats.J Pharmacol Exp Ther. 2003; 307: 9-16
- Lipopolysaccharide and trovafloxacin coexposure in mice causes idiosyncrasy-like liver injury dependent on tumor necrosis factor-alpha.Toxicol Sci. 2007; 100: 259-266
- Drug-induced autoimmune-like hepatitis.Dig Dis Sci. 2011; 56: 958-976
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Published online: August 05, 2013
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